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2010/01/27
HOXB9 promotes breast cancer progression
Aberrant expression of transcription factors has been implicated in tumorigenesis. Investigators from the Cell Biology and Stem Cells Unit at CIC bioGUNE and groups at Massachusetts General Hospital and Harvard Medical School have shown that HOXB9 is overexpressed in breast cancer and implicated in increased cell motility and acquisition of mesenchymal phenotypes.
The work was published in PNAS on January 19th, 2010.