Publications

2026

A pilot genome-wide association study of collagen deposition in collagenous colitis
Di Lorenzo, B; Zheng, TH; Rieder, F; Colombel, JF; Peter, I; Kupcinskas, J; Ohlsson, B; Cassado, CF; Zabana, Y; Münch, A; Janciauskas, D; Gordon, IO; DAmato, M; Roda, G;
GASTROENTEROLOGY REPORT
2026

Rational design of heparin antagonist: Guanidine-based mimetics unveil key carbohydrate-carbohydrate interactions
Chandra, A; Gimeno, A; Payá-García, M; Bhoge, PR; Mahida, V; Jiménez-Barbero, J; Kikkeri, R;
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2026

From Lab to Industry: Advancing the Translational Potential of Extracellular Vesicles Through the ISEV Translation, Regulation and Advocacy Committee (ISEV-TRA)
Gurriaran-Rodriguez, U; Bussolati, B; Gimona, M; Glebov, K; Fujita, Y; Marcilla, A; Neri, C; Fu, QL; Das, S; Pluchino, S; Zarovni, N; Salomon, C; Witwer, K; Falcon-Perez, JM;
JOURNAL OF EXTRACELLULAR VESICLES
2026

Polyamine-dependent metabolic shielding regulates alternative splicing
Zabala-Letona, A; Pujana-Vaquerizo, M; Martinez-Laosa, B; Ponce-Rodriguez, M; Garcia-Longarte, S; Mendizabal, I; Gimeno, A; Rogalska, M; Tan, J; Cabrera, D; Van Liempd, S; Ximenez-Embun, P; ...
NATURE
2026

Multi-omics biomarkers for predicting treatment response in inflammatory bowel disease
Baldan-Martin, M; Azkargorta, M; Aransay, AM; Gil-Redondo, R; Moreno-Indias, I; Iloro, I; González, PJM; Soleto,; Suarez-Trujillo, F; Ramírez, C; Lucendo, A; Gutiérrez, CR; Casbas, AG; Arranz, ...
JOURNAL OF CROHNS & COLITIS
2026

Systems biology-driven miR-mRNA integration identifies potential steroid-refractoriness biomarkers in ulcerative colitis and reveals a conserved mechanism across species
Mir, IG; Suau, R; Naves, JE; Bernal, C; Clua, L; Monfort-Ferré, D; Pluvinet, R; Herrero, JFS; Segú, C; Aransay, AM; Ciria, MM; Sumoy, L; Serena, C; Moral, ED; Almero, JM;
JOURNAL OF CROHNS & COLITIS
2026

A protein signature for prediction of disease course in newly diagnosed Ulcerative Colitis
Grännö, O; Bergemalm, D; Salomon, B; Lindqvist, CM; Hedin, CR; Carlson, M; Erik, A; Strid, H; Carsstens, A; Hjortswang, H; Lundström, ML; Hreinsson, JP; Almer, S; Eriksson, C; Keita, Å; Magnusson, ...
JOURNAL OF CROHNS & COLITIS
2026

Incorporating Mn2+ions in bioactive sol-gel coatings: Impact on cell adhesion, inflammation and bone regeneration
Arias-Mainer, C; Romero-Gavilán, F; Abenia-Artigas, L; García-Arnáez,; Amorrotu, O; Azkargorta, M; Elortza, F; Gurruchaga, M; Goni, I; Suay, J;
COLLOIDS AND SURFACES B-BIOINTERFACES
2026

Non-targeted lipidomic profiling reveals distinct molecular signatures in inflammatory bowel disease: Discovery and validation in two inception cohorts
Salihovic, S; Oyås, O; Hansen, SH; Salomon, B; Bergemalm, D; Hjortswang, H; Grännö, O; Hedin, CR; Eriksson, C; Holm, K; Aabrekk, TB; DAmato, M; Oresic, M; Detlie, TE; Kristensen,; Keita, Å; ...
JOURNAL OF CROHNS & COLITIS
2026

Serum and urine metabolomic-lipoprotein signatures predict Inflammatory Bowel Disease treatment response to biologics and JAK-inhibitors
González, PJM; Baldan-Martin, M; Gil-Redondo, R; Soleto,; Orejudo, M; Ramírez, C; Lucendo, A; Rodríguez, C; Casbas, AG; Arranz, EM; Bujanda, L; Rodríguez-Lago,; Garcia, RMD; Flores, EI; san ...
JOURNAL OF CROHNS & COLITIS
2026

Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility
Díaz-Muñoz, C; Bozzarelli, I; Lopera-Maya, EA; Belbasis, L; Lo Faro, V; Tavares, LC; Heredia-Fernández, F; Di Lorenzo, B; Sinha, T; Blanco, CE; Favé, MJ; Awadalla, P; Walters, RG; Bonfiglio, ...
GUT
2026

Dissecting Tin-Based Activation and Anomerization Pathways in Carbohydrate Chemistry
Navo, CD; Moure, MJ; Valverde, P; Poveda, A; Jimenez-Oses, G; Jimenez-Barbero, J; Franconetti, A;
ACS OMEGA
2026

Rapid generation of prion disease models using AAV-delivered PrP variants in knockout mice
San-Juan-Ansoleaga, M; Fernández-Muñoz, E; Charco, JM; Vidal, E; Herrero-Martínez, D; Galarza-Ahumada, J; Sampedro-Torres-Quevedo, C; Giler, S; Geijo, M; González-Aseguinolaza, G; Eraña, H; ...
BRAIN PATHOLOGY
2026

Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid
Correia, SD; Schmitz, M; Hermann, P; Goebel, S; Gerecke, J; Lingor, P; Maass, F; Fischer, AL; Canaslan, S; Eraña, H; Castilla, J; Correia, AD; Zerr, I;
ACTA NEUROPATHOLOGICA COMMUNICATIONS
2026

Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt
Pellon, A; Nasab, SDS; Bidkhori, G; Griffiths, JS; Vaga, S; Begum, N; Blagojevic, M; Sigh, NK; Kotowicz, NK; Uzochukwu, I; Le Guennec, A; Henley-Smith, R; Gregson-Williams, H; Clasen, F; Pryce, ...
SCIENCE ADVANCES
2026

Spatial Profiling Reveals Distinct Early Spatial, Cellular and Genetic Features in Presymptomatic Ulcerative Colitis (PISCIS study)
Mateos, B; Mehandru, S; Rodríguez-Lago,; Marigorta, UM;
JOURNAL OF CROHNS & COLITIS
2026

Structural basis of glycoform selectivity in prion strains
Peccati, F;
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
2026

Defining the reference proteomes for small extracellular vesicles and non-vesicular components
Morales-Sanfrutos, J; Etxeberria-Ugartemendia, J; Barroso-Gomila, O; González, E; Sendino, M; Ximénez-Embún, P; García, F; Zarzuela, E; Falcón-Pérez, JM; Peinado, H; Muñoz, J;
NATURE CELL BIOLOGY
2026

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness
Eraña, H; Vidal, E; Fernández-Borges, N; Charco, JM; Díaz-Domínguez, CM; Sampedro-Torres-Quevedo, C; San-Juan-Ansoleaga, M; Fernández-Muñoz, E; Galarza-Ahumada, J; Pérez-Castro, MA; Gonçalves-Anjo, ...
ACTA NEUROPATHOLOGICA COMMUNICATIONS
2026

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains
Eraña, H; Vidal, E; Fernández-Borges, N; Charco, JM; Díaz-Domínguez, CM; Sampedro-Torres-Quevedo, C; Galarza-Ahumada, J; Fernández-Muñoz, E; San-Juan-Ansoleaga, M; Pérez-Castro, MA; Gonçalves-Anjo, ...
BRAIN PATHOLOGY
2026

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases
Masone, A; Grasso, A; Comerio, L; Bruno, R; Lavigna, G; Vanni, I; DAgostino, C; Orrù, CD; Caughey, B; Altmeppen, HC; Castilla, J; Giaccone, G; Tagliavini, F; Di Bari, MA; Nonno, R; Chiesa, R;
ACTA NEUROPATHOLOGICA
2026

On the Molecular Basis of the Hypersaline Adaptation of Halophilic Proteins
Ortega-Quintanilla, G; Millet, O;
JOURNAL OF MOLECULAR BIOLOGY
2026

A novel diagnostic serum protein signature for pediatric inflammatory bowel disease
Mathisen, CBW; Nyström, N; Bazov, I; Oyås, O; Zucknick, M; Andersen, S; Olbjorn, C; Perminow, G; Kristensen, VA; Opheim, R; DAmato, M; Carlson, M; Hedin, CRH; Keita, ÅV; Lindqvist, CM; Magnusson, ...
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
2026

N-Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction
Jiménez-Sánchez, L; Ruiz-López, P; González-García, P; Purhonen, J; Martínez-Gálvez, JM; López-Herrador, S; Corral-Sarasa, J; Díaz-Casado, ME; Venegas, C; Santos-Pérez, I; Olivieri, E; Rojas, ...
ACTA PHYSIOLOGICA
2026

Aminolevulinate inhibition of human coproporphyrinogen oxidase clarifies coproporphyrin III accumulation in porphyrias
Schedlbauer, A; Kratzwald, S; Gómez-Galán, M; Gil-Martínez, J; San Juan, I; Pereira-Ortuzar, T; Lopitz-Otsoa, F; Fernandez-Ramos, D; Mato, JM; Millet, O;
BIOSCIENCE REPORTS
2026

Updating MISEV: When, What, How, and Why?
Akbar, N; Burger, D; Bussolati, B; Buzás, EI; Carney, RP; Cho, Y-; Driedonks, TAP; Falcon-Perez, JM; Fujita, Y; Goberdhan, DC; Hendrix, A; Huang, YY; Mathivanan, S; Mahoney, MG; Mohanty, S; ...
JOURNAL OF EXTRACELLULAR VESICLES
2026

Immune and Endothelial-Related Extracellular Vesicles Are Associated with Corticosteroid Response and Mortality in Alcohol-Associated Hepatitis
Guinart-Cuadra, A; Brujats, A; Szafranska, J; Guerrero, R; Dinamarca, F; Cantó, E; Poca, M; Román, E; Sánchez-Ardid, E; Fajardo, J; Camps, M; Mulet, M; Soriano, G; Escorsell, A; Falcon-Perez, ...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2026

Fusobacterium nucleatum Lipopolysaccharides Disrupt the Interaction of Siglec-7 to Sialoglycans Expressed on Mammalian Cells
Ali, MGA; Psomiadou, V; Martin, MT; Lamprinaki, D; Nieto-Fabregat, F; Sobczak, K; Macauley, MS; Ereno-Orbea, J; De Castro, C; Silipo, A; Boltje, TJ; Juge, N;
JACS AU
2026

Crosstalk between the extracellular matrix and breast stem cells in health and disease
Siragusa, G; Fernandez-de-Larrea, L; Meesters, N; Vivanco, MD;
FEBS JOURNAL
2026

A small molecule inhibitor of ARF GTPase protein 1 limits liver and colon cancer cell growth and metastasis
Peng, H; Chhimwal, J; Fan, W; Wang, JH; Barbier-Torres, L; Sinha, S; Chatterjee, A; Zhang, Y; Tomasi, ML; Mato, JM; Murali, R; Lu, SC;
CELL DEATH & DISEASE
2026

Linking hubness, embryonic neurogenesis, transcriptomics and diseases in human brain networks
Diez, I; Garcia-Moreno, F; Carral-Sainz, N; Stramaglia, S; Nieto-Reyes, A; DAmato, M; Cortes, JM; Bonifazi, P;
JOURNAL OF COMPUTATIONAL NEUROSCIENCE
2026

Trefoil Factor-3 Is a Hypoxia-Triggered Pro-Tumorigenic Factor in Hepatoblastoma
Martínez-Pérez, LA; Latasa, MU; Uriarte, I; López-Pascual, A; Elurbide, J; Strnad, P; Frankova, S; Sticova, E; Fabian, O; Arechederra, M; Santamaria, E; Argemi, J; Sangro, B; Foglia, B; Parola, ...
LIVER INTERNATIONAL
2026

Obestatin: canonical and unexpected functions
Santos-Zas, I; Gurriaran-Rodriguez, U; Cid-Diaz, T; Leal-Lopez, S; Casanueva, FF; Pazos-Randulfe, Y; Camiña, JP;
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
2026

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol
Sánchez-Gordón, G; Plans-Beriso, E; Barahona-López, C; Anta, B; Millet, O; Fernández-Navarro, P; de Larrea-Baz, NF; Castelló-Pastor, A;
HEALTH SCIENCE REPORTS
2026

A guide to mapping ubiquitin and ubiquitin-like E3 ligases to their substrates
Merino-Cacho, L; Guinea-Pérez, C; Pozo-Rodríguez, M; Cano-López, S; Ramirez, J; Barroso-Gomila, O; Mayor, U; Sutherland, JD; Barrio, R;
FEBS JOURNAL
2026

Aspartate availability drives differential engagement of the malate-aspartate shuttle
Brunner, JS; Bridgeman, AE; Jackson, BT; Chakraborty, S; Fagoaga-Eugui, M; Paras, KI; Xie, A; Arnold, PK; Losner, J; Finley, LWS;
MOLECULAR CELL
2026

Tertiary and quaternary structure remodeling by occupancy of the substrate binding pocket in a large glutamate dehydrogenase
Lázaro, M; Chamorro, N; López-Alonso, JP; Charro, D; Rasia, RM; Jiménez-Osés, G; Valle, M; Lisa, M;
PROTEIN SCIENCE
2026

Exploring the binding properties and activities of ancestral expansins
Jabalera, Y; Marin-Peña, AJ; Wagner, E; Cosgrove, DJ; Master, ER; Perez-Jimenez, R;
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2026

Tachykinin signaling defines distinct populations of glia in the enteric nervous system
Muppirala, AN; Mitchel, PE; Courtney, E; Debnath, S; DAlessandro, LR; Mani, N; Dadabhoy, M; Robinson, A; Díaz-Muñoz, C; Paraskevopoulou, MD; DAmato, M; Gould, TW; Rao, M;
NEURON
2026

Lipidomics uncovers metabolic manifestations related to liver steatosis and low-grade systemic inflammation in diet-treated hereditary fructose intolerance patients
de las Heras, J; Suarez, MU; Mercado-Gómez, M; Gracianteparaluceta, LU; Buqué, X; Alonso, C; Serrano-Macia, M; Alcalde, C; Cano, A; González-Recio, I; Goikoetxea-Usandizaga, N; Mora, E; Belanger-Quintana, ...
CLINICAL NUTRITION
2026

Plagl1 regulates the retinal progenitor cell to Müller glial cell transition
Touahri, Y; Pak, A; David, LA; Hanna, J; Liu, H; Xiao, YC; Belfiore, L; Ilnytskyy, Y; van Oosten, E; Tachibana, N; Adnani, L; Zhao, JY; Hoffman, M; Dixit, R; Zinyk, D; Guidos, CJ; Enzmann, V; ...
PLOS GENETICS
2026

Adaptive tuning of Hamiltonian Monte Carlo methods
Akhmatskaya, E; Nagar, L; Carrillo, JA; Balmacz, LG; Inouzhe, H; Pazos, MP; Alvarez, MXR;
APPLIED MATHEMATICAL MODELLING
2026

Transmission Ratio Distortion in Genetic Prion Diseases: Clarifying Methodological Considerations
Kortazar-Zubizarreta, I; Manero-Azua, A; Eraña, H; Castilla, J; de Nanclares, GP;
EUROPEAN JOURNAL OF NEUROLOGY
2026

Urine Proteomics in Cirrhosis and Acute Kidney Injury: Insights Into the Pathogenesis of Hepatorenal Syndrome
Napoleone, L; Azkargorta, M; Sidorova, J; Juanola, A; Pose, E; Ginès, P; Barcelona Clinnic Liver Cirrhosis Grp;
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2026

From molecular mechanisms of glycosphingolipid function to bio-therapeutic applications
Saha, A; Johannes, L;
CELLULAR AND MOLECULAR LIFE SCIENCES
2026

Ring opening, conformational analysis and NagZ inhibition of a GlcNAc-configured iminosugar-derived aziridine
Auberger, N; El-Araby, AM; Van Tran, T; Feltzer, R; Poveda, A; Jiménez-Barbero, J; Mobashery, S; Blériot, Y;
CARBOHYDRATE RESEARCH
2026

Hepatic HuR modulates glucose metabolism through the C/EBPβ/PCK1 pathway
Lachiondo-Ortega, S; González-Recio, I; Bravo, M; Gonzalez-Rellan, MJ; Sanz-Parra, A; Porteiro, B; Goikoetxea-Usandizaga, N; Rejano-Gordillo, CM; Zapata-Pavas, LE; Peña-Sanfélix, P; Conter, ...
MOLECULAR METABOLISM
2026

miR-122 Deficiency in Mice Enhances Regeneration in Healthy Liver but Drives Pathological Repair and Functional Decline in Fibrotic Liver
Ribera, J; Cardona-Simó, A; Portolés, I; Samper, E; Boix, L; Fabregat-Bolufer, AB; Fernández-Galán, E; Rodríguez-Garcia, M; Azkargorta, M; Elortza, F; Celton-Morizur, S; Desdouets, C; Melgar-Lesmes, ...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2026

Results of the Ninth Scientific Workshop of the European Crohn's and Colitis Organisation (ECCO): artificial intelligence in endoscopy, radiology, and histology in inflammatory bowel disease diagnostics
Mookhoek, A; Sinonquel, P; Allocca, M; Carter, D; Ensari, A; Iacucci, M; Kopylov, U; Verstockt, B; Baumgart, DC; Noor, NM; El-Hussuna, A; Sahnan, K; Marigorta, UM; Noviello, D; Bossuyt, P; Pellino, ...
JOURNAL OF CROHNS & COLITIS
2026

Results of the Ninth Scientific Workshop of the European Crohn's and Colitis Organisation (ECCO): artificial intelligence in IBD: regulatory and methodological considerations
Noor, NM; Daperno, M; de Laffolie, J; Mookhoek, A; Sinonquel, P; Kopylov, U; Verstockt, B; El-Hussuna, A; Sahnan, K; Allocca, M; Bossuyt, P; Carter, D; Ensari, A; Iacucci, M; Marigorta, UM; ...
JOURNAL OF CROHNS & COLITIS
2026

Results of the Ninth Scientific Workshop of the European Crohn's and Colitis Organisation (ECCO): artificial intelligence in IBD surgery-opportunities and limitations
El-Hussuna, A; Pellino, G; Soriano, A; Sahnan, K; Mookhoek, A; Sinonquel, P; Allocca, M; Carter, D; Ensari, A; Iacucci, M; Kopylov, U; Verstockt, B; Baumgart, DC; Noor, NM; Marigorta, UM; Noviello, ...
JOURNAL OF CROHNS & COLITIS
2026

A quantitative metabolic signature of host response during SARS-CoV-2 infection and recovery
Ma, SY; Koplin, E; Shilts, MH; Voehler, M; Rachakonda, G; Gil-Redondo, R; Rajagopala, SV; Río, JS; Botta-Orfila, T; Sibila, O; Asad, M; Sehanobish, E; Jerschow, E; Phillips, E; Millet, O; Mallal, ...
ISCIENCE
2026

Results of the Ninth Scientific Workshop of the European Crohn's and Colitis Organisation (ECCO): Artificial Intelligence in medical management and precision medicine
Kopylov, U; Verstockt, B; Marigorta, UM; Noviello, D; Bossuyt, P; Mookhoek, A; Sinonquel, P; El-Hussuna, A; Sahnan, K; Baumgart, DC; Noor, NM; Allocca, M; Carter, D; Ensari, A; Iacucci, M; Pellino, ...
JOURNAL OF CROHNS & COLITIS
2026

Building a better gingival seal in dental implants: hydrothermal ion incorporation into titanium abutment surfaces
Abenia-Artigas, L; Arias-Mainer, C; Miquel, E; Lee, KN; Elortza, F; Azkargorta, M; Gurruchaga, M; Goni, I; Suay, J;
BIOMATERIALS ADVANCES
2026

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
Zink, A; Dai, DF; Wittich, A; Henke, MT; Pedrotti, G; Heiduschka, S; Santamaria, G; Pentimalli, TM; Brueser, C; Notopoulou, S; Umar, AR; Zhaivoron, A; Petersilie, L; Jerred, C; Bergmans, J; ...
CELL
2026

Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis
Novoa, E; Parracho, T; Inderhees, J; Rodriguez, A; Riobello, C; Iglesias-Moure, J; Fernández-Iglesias, A; Martinez-Martinez, S; Senra, A; Seoane, S; Fondevila, M; Iglesias, C; Cabaleiro, A; ...
CELL METABOLISM
2026

Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids
Menacho, C; Okawa, S; Alvarez-Merz, I; Wittich, A; Muñoz-Oreja, M; Lisowski, P; Martín, ML; Pentimalli, TM; Zakin, S; Thevandavakkam, M; Jerred, C; Lickfett, S; Petersilie, L; Rybak-Wolf, A; ...
NATURE COMMUNICATIONS
2026

Pharmacological strategies to enhance the response of hepatoblastoma to chemotherapy through MDR1 inhibition
Cives-Losada, C; Macias, RIR; Lozano, E; Zanatto, L; Sancho-Bru, P; Martinez-Chantar, ML; Avila, MA; Armengol, C; Cairo, S; Marin, JJG; Briz, O;
ACTA PHARMACOLOGICA SINICA
2026

Inhibition of the SerpinB3/protease-activated receptor 2 axis reduces liver cancer development and affects lipid metabolism
Guerra, P; Villano, G; Rejano-Gordillo, CM; Gil-Pitarch, C; Ruvoletto, M; Biasiolo, A; Quarta, S; Zapata-Pavas, LE; Peña-SanFelix, P; González-Recio, I; Goikoetxea-Usandizaga, N; Barrenechea-Barrenechea, ...
BRITISH JOURNAL OF CANCER
2026

Leveraging Glycan-Glycan Interactions to Tune the Conformation of Glycan Hairpins and Build Rigid 3D Architectures
Yadav, N; Vazquez-Mena, Y; Poveda, A; Weh, D; Jimenez-Barbero, J; Ogawa, Y; Delbianco, M;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2026

Fundamentals of Neurogastroenterology: Physiological Aspects and Clinical Implications
De Giorgio, R; Boeckxstaens, GE; Cryan, JF; DAmato, M; Dinning, PG; Hasler, WL; Vanuytsel, T; Houghton, LA;
GASTROENTEROLOGY
2026

Metabolic alterations driven by PFKFB3 upregulation confer resistance to trastuzumab in HER2-positive breast cancer.
Vincken, Roos; Pasco, Samuel T; Steri, Veronica; Bozal-Basterra, Laura; van IJcken, Wilfred F J; Carracedo, Arkaitz; Huylebroeck, Danny; Moasser, Mark M; Ruiz-Saenz, Ana;
BIOMEDICINE & PHARMACOTHERAPY
2026